Nicotinamide

 Nicotinamide is a very stable vitamin which offers a wide range of benefits.  is a component of NAD and NADP, essential coenzymes in ATP production, also having a central role in DNA repair and skin homeostasis.It is a significant niacin derivative, mainly occurring in many organisms. Nowadays, as a natural cosmetics ingredient, it is widely applied in skin and hair care products. is divided into  medical grade and  cosmetics grade.
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PRODUCTS DETAILS

Nicotinamide also known as Niacinamide,  vitamin B3 or Vitamin PP, is a water-soluble vitamin, belonging to the B group of vitamins, coenzyme I (nicotinamide adenine dinucleotide, NAD) and coenzyme II (nicotinamide adenine dinuclear The nicotinamide part of these two coenzyme structures in the human body has reversible hydrogenation and dehydrogenation characteristics, plays a hydrogen transfer role in biological oxidation, and can promote tissue respiration and biological oxidation. processes and metabolism, which are important for maintaining the integrity of normal tissues, especially the skin, digestive tract and nervous system. Nicotinamide is a very stable vitamin which offers a wide range of benefits. is a component of NAD and NADP, essential coenzymes in ATP production, also having a central role in DNA repair and skin homeostasis. It is a significant niacin derivative, mainly occurring in many organisms. can produce coenzyme Ⅰ and Ⅱ when it reacts with ribose, adenine and phosphoric acid. Also it boosts the synthesis of DNA, fats and proteins and improves the energy metabolism of cells. So it can greatly prevent melanin deposition, and reduce discoloration. It has an effective whitening function. Nowadays, as a natural cosmetics ingredient, it is widely applied in skin and hair care products.   Key Technical Parameters: Appearance White crystalline powder Assay 99.0~101.0% pH (10% aqueous solution) 5.5~7.5 Melting range 128.0~131.0℃ Residue on ignition ≤0.1%(wt%) Heavy metals ≤20ppm Identification Complies Readily carbonizable Complies Loss on drying ≤0.5% Application: • UV and blue light-stressed Skin Care • Helps protect from UV and blue light damage for beautiful and healthy looking skin • Reduces the appearance of lines and wrinkles • Improves the elasticity of the skin • Rebalances uneven skin tone • Reduces discoloration • Pollution Care • Protects against damage from urban pollutants for beautiful and healthy skin • Blemish Care • Blemish-free, shine-free, refined skin appearance • Resilience to external damage and reduced skin sensitivity • Well moisturized skin, comfortable skin feeling • PC shows skin lightening properties versus placebo in 3D skin model. Benefits: • Prevent melanin from depositing into keratinocytes Skin will darken when melanin is delivered to keratinocytes. But can act on generated melanin, and then efficiently prevent the transfer of 35% to 40% of melanin from melanocytes to horny cells. Hence, it can lessen excessive pigmentation. Clinical tests have suggested that face cream can obviously reduce the brown spots ‘ number and area. • Accelerate the metabolism of melanocytes is directly absorbed by cells owing to its small molecules. can penetrate the inner layer of the skin within 2 hours. Using to the skin can form energy molecules in human body quickly. It can penetrate the stratum corneum to the connective tissue and fibers between the dermis; and then it directly gets in the bottom of the cell to facilitate the metabolism of cells. • Promote synthesis of cortical proteins on skin synthesizes protein on the surface of skin. And it amends skin texture, and moisturizes skin. In 1990, European Patent 0-396-422 shows that it can whiten skin and exert sun block effect to add , 0.1% to 5% silicone compound and UVA, UVB sunscreen into the cream formulation.  

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